{"id":2678,"date":"2025-10-22T10:39:45","date_gmt":"2025-10-22T08:39:45","guid":{"rendered":"https:\/\/okuvision.de\/retinitis-pigmentosa-studienlage\/"},"modified":"2026-05-22T10:38:52","modified_gmt":"2026-05-22T08:38:52","slug":"retinitis-pigmentosa-studienlage","status":"publish","type":"page","link":"https:\/\/okuvision.de\/fr\/retinitis-pigmentosa-studienlage\/","title":{"rendered":"\u00c9tudes et recherche"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row unlock_row_content=\u00a0\u00bbyes\u00a0\u00bb row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb0&Prime; top_padding=\u00a0\u00bb0&Prime; bottom_padding=\u00a0\u00bb0&Prime; back_color=\u00a0\u00bbcolor-206913&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb126459&Prime; back_color_type=\u00a0\u00bbuncode-palette\u00a0\u00bb][vc_column width=\u00a0\u00bb1\/1&Prime;]\n<div id=\"cvc-hero_image-6a40caea6108b\" class=\"cvc-element cvc-hero-image cvc-hero-image--violet cvc-hero-image--headline-hl-xl cvc-hero-image--text-large cvc-pattern-top-right-pattern cvc-pattern-bottom-left-pattern\" role=\"region\" aria-label=\"Recherche et \u00e9tudes sur la r\u00e9tinite pigmentaire (RP)\">\n    \n    <!-- Background Patterns -->\n            <div class=\"cvc-hero-image__pattern cvc-hero-image__pattern--left\" aria-hidden=\"true\"><\/div>\n                <div class=\"cvc-hero-image__pattern cvc-hero-image__pattern--right\" aria-hidden=\"true\"><\/div>\n        \n    <!-- Content Container (max-width, centered) -->\n    <div class=\"cvc-hero-image__container\">\n        \n        <div class=\"cvc-hero-image__inner\">\n            <div class=\"cvc-hero-image__content\">\n                \n                                \n                                                        <h1 class=\"cvc-hero-image__headline font-714446 fontsize-431854\">\n                        Recherche et \u00e9tudes sur la r\u00e9tinite pigmentaire (RP)                    <\/h1>\n                                \n                <div class=\"cvc-hero-image__text-wrapper\">\n                                            <div class=\"cvc-hero-image__text-content text-lead\">\n                            <p>Cette page regroupe la recherche actuelle sur la r\u00e9tinite pigmentaire \u2013 de la g\u00e9n\u00e9tique et des param\u00e8tres d\u2019\u00e9volution jusqu\u2019aux donn\u00e9es cliniques sur la TES avec OkuStim\u00ae.<\/p>\n                        <\/div>\n                                        \n                                    <\/div>\n                \n                                \n            <\/div>\n            \n            <!-- Image (breaks out to right edge) -->\n                            <div class=\"cvc-hero-image__image\">\n                    <img width=\"2008\" height=\"1339\" src=\"https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung.webp\" class=\"attachment-full size-full\" alt=\"Studien und Forschung\" loading=\"lazy\" decoding=\"async\" srcset=\"https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung.webp 2008w, https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung-300x200.webp 300w, https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung-1024x683.webp 1024w, https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung-768x512.webp 768w, https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung-1536x1024.webp 1536w, https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung-350x233.webp 350w, https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung-uai-720x480.webp 720w, https:\/\/okuvision.de\/wp-content\/uploads\/2025\/12\/OV_Studien-und-Forschung-uai-1032x688.webp 1032w\" sizes=\"auto, (max-width: 2008px) 100vw, 2008px\" \/>                <\/div>\n                    <\/div>\n        \n    <\/div>\n    \n<\/div>\n\n\n[\/vc_column][\/vc_row][vc_row row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb2&Prime; top_padding=\u00a0\u00bb3&Prime; bottom_padding=\u00a0\u00bb0&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb220104&Prime;][vc_column width=\u00a0\u00bb1\/1&Prime;]\n<div id=\"cvc-anchor-nav-6a40caea61912\" class=\"cvc-element cvc-anchor-navigation cvc-anchor-navigation--violet\">\n    <div class=\"cvc-anchor-navigation__container\">\n        <nav class=\"cvc-anchor-navigation__nav\" \n             role=\"navigation\" \n             aria-label=\"Anchor navigation\">\n            \n            <ul class=\"cvc-anchor-navigation__list\">\n                                                        <li class=\"cvc-anchor-navigation__item\">\n                        <a href=\"#relevanz-forschung\" \n                           id=\"cvc-anchor-nav-6a40caea61912-link-1\"\n                           class=\"cvc-anchor-navigation__link cvc-anchor-navigation__link--active\"\n                           data-smooth-scroll\n                           aria-current=\"location\">\n                            <span class=\"cvc-anchor-navigation__label\">Pertinence de la recherche<\/span>\n                                                            <span class=\"cvc-sr-only\">(section actuelle)<\/span>\n                                                    <\/a>\n                    <\/li>\n                                                        <li class=\"cvc-anchor-navigation__item\">\n                        <a href=\"#genetik-vererbung\" \n                           id=\"cvc-anchor-nav-6a40caea61912-link-2\"\n                           class=\"cvc-anchor-navigation__link\"\n                           data-smooth-scroll\n                           >\n                            <span class=\"cvc-anchor-navigation__label\">G\u00e9n\u00e9tique et h\u00e9r\u00e9dit\u00e9<\/span>\n                                                    <\/a>\n                    <\/li>\n                                                        <li class=\"cvc-anchor-navigation__item\">\n                        <a href=\"#therapieansaetze\" \n                           id=\"cvc-anchor-nav-6a40caea61912-link-3\"\n                           class=\"cvc-anchor-navigation__link\"\n                           data-smooth-scroll\n                           >\n                            <span class=\"cvc-anchor-navigation__label\">Approches th\u00e9rapeutiques<\/span>\n                                                    <\/a>\n                    <\/li>\n                                                        <li class=\"cvc-anchor-navigation__item\">\n                        <a href=\"#studien\" \n                           id=\"cvc-anchor-nav-6a40caea61912-link-4\"\n                           class=\"cvc-anchor-navigation__link\"\n                           data-smooth-scroll\n                           >\n                            <span class=\"cvc-anchor-navigation__label\">\u00c9tudes cliniques sur la TES<\/span>\n                                                    <\/a>\n                    <\/li>\n                            <\/ul>\n        <\/nav>\n    <\/div>\n<\/div>\n[\/vc_column][\/vc_row][vc_row row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb2&Prime; top_padding=\u00a0\u00bb3&Prime; bottom_padding=\u00a0\u00bb0&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb206058&Prime; row_name=\u00a0\u00bbRelevanz Forschung\u00a0\u00bb][vc_column width=\u00a0\u00bb1\/1&Prime;][vc_row_inner][vc_column_inner width=\u00a0\u00bb2\/3&Prime;][vc_custom_heading text_font=\u00a0\u00bbfont-714446&Prime; text_size=\u00a0\u00bbfontsize-914237&Prime; text_weight=\u00a0\u00bb300&Prime; uncode_shortcode_id=\u00a0\u00bb742058&Prime;]Pourquoi la recherche<br \/>est essentielle[\/vc_custom_heading][\/vc_column_inner][vc_column_inner column_width_percent=\u00a0\u00bb100&Prime; gutter_size=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; shift_x=\u00a0\u00bb0&Prime; shift_y=\u00a0\u00bb0&Prime; shift_y_down=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; medium_visibility=\u00a0\u00bbyes\u00a0\u00bb medium_width=\u00a0\u00bb0&Prime; mobile_visibility=\u00a0\u00bbyes\u00a0\u00bb mobile_width=\u00a0\u00bb0&Prime; width=\u00a0\u00bb1\/3&Prime; uncode_shortcode_id=\u00a0\u00bb542260&Prime;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner column_width_percent=\u00a0\u00bb100&Prime; gutter_size=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; shift_x=\u00a0\u00bb0&Prime; shift_y=\u00a0\u00bb0&Prime; shift_y_down=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; medium_visibility=\u00a0\u00bbyes\u00a0\u00bb medium_width=\u00a0\u00bb0&Prime; mobile_visibility=\u00a0\u00bbyes\u00a0\u00bb mobile_width=\u00a0\u00bb0&Prime; width=\u00a0\u00bb1\/3&Prime; uncode_shortcode_id=\u00a0\u00bb163215&Prime;][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb2\/3&Prime;][vc_column_text uncode_shortcode_id=\u00a0\u00bb122633&Prime;]La r\u00e9tinite pigmentaire (RP) est une maladie r\u00e9tinienne h\u00e9r\u00e9ditaire pouvant entra\u00eener une perte de vision au fil des ann\u00e9es. La recherche aide \u00e0 comprendre les m\u00e9canismes de la maladie, \u00e0 mesurer son \u00e9volution et \u00e0 \u00e9valuer les options th\u00e9rapeutiques \u2013 avec un b\u00e9n\u00e9fice tangible pour les patients, leurs proches et le syst\u00e8me de sant\u00e9. Les revues d\u00e9crivent non seulement les impacts m\u00e9dicaux, mais aussi les cons\u00e9quences \u00e9conomiques et psychosociales de la RP. Typique de la RP : la c\u00e9cit\u00e9 nocturne aux stades pr\u00e9coces, puis un r\u00e9tr\u00e9cissement du champ visuel jusqu\u2019\u00e0 la \u00ab vision en tunnel \u00bb \u2013 cette \u00e9volution clinique est bien d\u00e9crite et aide \u00e0 choisir des crit\u00e8res d\u2019\u00e9valuation pertinents dans les \u00e9tudes. Conclusion : la recherche constitue la base d\u2019attentes r\u00e9alistes et de meilleures d\u00e9cisions de prise en charge.<sup>1<\/sup>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb2&Prime; top_padding=\u00a0\u00bb3&Prime; bottom_padding=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb944703&Prime; row_name=\u00a0\u00bbgenetik-vererbung\u00a0\u00bb][vc_column width=\u00a0\u00bb1\/1&Prime;][vc_row_inner][vc_column_inner width=\u00a0\u00bb2\/3&Prime;][vc_custom_heading text_font=\u00a0\u00bbfont-714446&Prime; text_size=\u00a0\u00bbfontsize-914237&Prime; text_weight=\u00a0\u00bb300&Prime; uncode_shortcode_id=\u00a0\u00bb137717&Prime;]G\u00e9n\u00e9tique et h\u00e9r\u00e9dit\u00e9 \u2014 les bases[\/vc_custom_heading][\/vc_column_inner][vc_column_inner column_width_percent=\u00a0\u00bb100&Prime; gutter_size=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; shift_x=\u00a0\u00bb0&Prime; shift_y=\u00a0\u00bb0&Prime; shift_y_down=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; medium_visibility=\u00a0\u00bbyes\u00a0\u00bb medium_width=\u00a0\u00bb0&Prime; mobile_visibility=\u00a0\u00bbyes\u00a0\u00bb mobile_width=\u00a0\u00bb0&Prime; width=\u00a0\u00bb1\/3&Prime; uncode_shortcode_id=\u00a0\u00bb542260&Prime;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner column_width_percent=\u00a0\u00bb100&Prime; gutter_size=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; shift_x=\u00a0\u00bb0&Prime; shift_y=\u00a0\u00bb0&Prime; shift_y_down=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; medium_visibility=\u00a0\u00bbyes\u00a0\u00bb medium_width=\u00a0\u00bb0&Prime; mobile_visibility=\u00a0\u00bbyes\u00a0\u00bb mobile_width=\u00a0\u00bb0&Prime; width=\u00a0\u00bb1\/3&Prime; uncode_shortcode_id=\u00a0\u00bb163215&Prime;][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb2\/3&Prime;][vc_column_text uncode_shortcode_id=\u00a0\u00bb366320&Prime;]La RP pr\u00e9sente une grande diversit\u00e9 g\u00e9n\u00e9tique : les synth\u00e8ses d\u00e9crivent des formes dues \u00e0 des mutations dans \u2265 80 g\u00e8nes ; la transmission est principalement autosomique r\u00e9cessive (~20 %), autosomique dominante (10\u201320 %) ou li\u00e9e \u00e0 l\u2019X (~10 %), et il existe \u00e9galement des cas sporadiques. Le diagnostic g\u00e9n\u00e9tique fournit des indications importantes pour le conseil, l\u2019\u00e9ligibilit\u00e9 aux \u00e9tudes et \u2013 pour des sous-types appropri\u00e9s \u2013 des th\u00e9rapies cibl\u00e9es.<sup>2<\/sup>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row unlock_row_content=\u00a0\u00bbyes\u00a0\u00bb row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb0&Prime; top_padding=\u00a0\u00bb0&Prime; bottom_padding=\u00a0\u00bb0&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb187729&Prime; row_name=\u00a0\u00bbtherapieansaetze\u00a0\u00bb][vc_column width=\u00a0\u00bb1\/1&Prime;]\n<div id=\"cvc-cta-6a40caea61a9f\" class=\"cvc-element cvc-cta cvc-cta--headline-hl-xl cvc-cta--text-regular cvc-cta--without-image\" role=\"region\" aria-label=\"Approches th\u00e9rapeutiques\nen recherche\">\n    \n    <!-- Image Area with Pattern (only for \"Mit Bild\" variant with actual image) -->\n        \n    <!-- Dark Background Content Area (SINGLE BLOCK for both variants) -->\n    <div class=\"cvc-cta__dark-wrapper style-color-jevc-bg\">\n        \n        <!-- Pattern Top Right - nur f\u00fcr \"Ohne Bild\" Variante -->\n                    <div class=\"cvc-cta__pattern cvc-cta__pattern--top-right\" aria-hidden=\"true\"><\/div>\n                \n        <!-- Pattern Bottom Left - f\u00fcr beide Varianten -->\n        <div class=\"cvc-cta__pattern cvc-cta__pattern--bottom-left\" aria-hidden=\"true\"><\/div>\n        \n        <!-- Content Container (max-width 1200px, centered) -->\n        <div class=\"cvc-cta__container\">\n            <div class=\"cvc-cta__content style-dark\">\n                \n                                    <h2 class=\"cvc-cta__headline text-color-233806-color font-714446 fontsize-431854\">\n                        Approches th\u00e9rapeutiques<br \/><br \/>\nen recherche                    <\/h2>\n                                \n                <div class=\"cvc-cta__text-wrapper\">\n                                            <div class=\"cvc-cta__text uncode_text_column\">\n                            <p>La litt\u00e9rature internationale d\u00e9crit plusieurs approches :<\/p>\n<ul>\n<li>Th\u00e9rapie g\u00e9nique : pour les dystrophies r\u00e9tiniennes h\u00e9r\u00e9ditaires associ\u00e9es \u00e0 RPE65, une th\u00e9rapie g\u00e9nique est autoris\u00e9e (voretigene neparvovec) ; des documents de r\u00e9f\u00e9rence et d\u2019\u00e9valuation confirment le b\u00e9n\u00e9fice clinique chez des patients s\u00e9lectionn\u00e9s de mani\u00e8re appropri\u00e9e.<sup>1<\/sup><\/li>\n<li>Approches cellulaires : l\u2019objectif est de r\u00e9g\u00e9n\u00e9rer ou de stabiliser \u00e0 terme les zones r\u00e9tiniennes endommag\u00e9es (actuellement principalement dans le cadre d\u2019\u00e9tudes).<sup>1<\/sup><\/li>\n<li>Optog\u00e9n\u00e9tique et implants r\u00e9tiniens : des approches visant \u00e0 r\u00e9activer les circuits r\u00e9tiniens r\u00e9siduels et \u00e0 compenser certaines fonctions \u00e0 un stade avanc\u00e9 de la maladie \u2014 principalement encore dans le cadre d\u2019\u00e9tudes cliniques.<sup>1<\/sup><\/li>\n<\/ul>\n<p>Pourquoi les \u00e9tudes mesurent-elles souvent le champ visuel ? Dans la RP, la vision p\u00e9riph\u00e9rique est particuli\u00e8rement touch\u00e9e. La surface de r\u00e9tine avec des photor\u00e9cepteurs intacts (VFA, visual field area) diminue de fa\u00e7on exponentielle avec le temps. Des travaux rapportent des diminutions annuelles (ADR, annual decline rate) d\u2019environ 5 \u00e0 17 %, selon la m\u00e9thode de mesure.<sup>2<\/sup><\/p>\n                        <\/div>\n                                        \n                                            <div class=\"cvc-cta__buttons\" role=\"group\" aria-label=\"Aktionen\">\n                                                        \n                                                            <a href=\"\/fr\/retinitis-pigmentosa-therapie\/\" \n                                   class=\"oku-button oku-button-md oku-button-white cvc-cta__button cvc-cta__button--secondary\"\n                                                                                                         aria-label=\"En savoir plus sur les \u00e9tudes TES et la th\u00e9rapie\">\n                                    <span>En savoir plus sur les \u00e9tudes TES et la th\u00e9rapie<\/span>\n                                    <i class=\"fa fa-arrow-right2\" aria-hidden=\"true\"><\/i>\n                                <\/a>\n                                                    <\/div>\n                                    <\/div>\n                \n            <\/div>\n        <\/div>\n        \n    <\/div>\n    \n<\/div>\n[\/vc_column][\/vc_row][vc_row row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb2&Prime; top_padding=\u00a0\u00bb3&Prime; bottom_padding=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb892533&Prime; row_name=\u00a0\u00bbstudien\u00a0\u00bb][vc_column width=\u00a0\u00bb1\/1&Prime;][vc_row_inner][vc_column_inner width=\u00a0\u00bb2\/3&Prime;][vc_custom_heading text_font=\u00a0\u00bbfont-714446&Prime; text_size=\u00a0\u00bbfontsize-914237&Prime; text_weight=\u00a0\u00bb300&Prime; uncode_shortcode_id=\u00a0\u00bb101376&Prime;]\u00c9tudes cliniques sur la th\u00e9rapie TES avec OkuStim\u00ae[\/vc_custom_heading][\/vc_column_inner][vc_column_inner column_width_percent=\u00a0\u00bb100&Prime; gutter_size=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; shift_x=\u00a0\u00bb0&Prime; shift_y=\u00a0\u00bb0&Prime; shift_y_down=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; medium_visibility=\u00a0\u00bbyes\u00a0\u00bb medium_width=\u00a0\u00bb0&Prime; mobile_visibility=\u00a0\u00bbyes\u00a0\u00bb mobile_width=\u00a0\u00bb0&Prime; width=\u00a0\u00bb1\/3&Prime; uncode_shortcode_id=\u00a0\u00bb542260&Prime;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner column_width_percent=\u00a0\u00bb100&Prime; gutter_size=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; shift_x=\u00a0\u00bb0&Prime; shift_y=\u00a0\u00bb0&Prime; shift_y_down=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; medium_visibility=\u00a0\u00bbyes\u00a0\u00bb medium_width=\u00a0\u00bb0&Prime; mobile_visibility=\u00a0\u00bbyes\u00a0\u00bb mobile_width=\u00a0\u00bb0&Prime; width=\u00a0\u00bb1\/3&Prime; uncode_shortcode_id=\u00a0\u00bb163215&Prime;][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb2\/3&Prime;][vc_column_text uncode_shortcode_id=\u00a0\u00bb758616&Prime;]La stimulation \u00e9lectrique transcorn\u00e9enne (TES) stimule la surface de l\u2019\u0153il \u00e0 l\u2019aide de faibles courants alternatifs. L\u2019objectif est d\u2019activer les m\u00e9canismes de protection cellulaires de la r\u00e9tine afin de pr\u00e9server plus longtemps sa fonction. Dans une \u00e9tude interventionnelle randomis\u00e9e men\u00e9e sur 12 mois (application hebdomadaire, traitement d\u2019un seul \u0153il), la perte du champ visuel \u00e9tait plus faible dans les yeux trait\u00e9s \u2014 avec un effet dose-d\u00e9pendant (plus l\u2019intensit\u00e9 du courant \u00e9tait \u00e9lev\u00e9e, plus le b\u00e9n\u00e9fice observ\u00e9 \u00e9tait important).2  <\/p>\n<p><b>S\u00e9curit\u00e9 : <\/b>dans l\u2019analyse publi\u00e9e, les effets ind\u00e9sirables \u00e9taient majoritairement l\u00e9gers et transitoires, le plus souvent une s\u00e9cheresse oculaire, rapidement am\u00e9lior\u00e9e par des larmes artificielles ; aucune augmentation des effets ind\u00e9sirables graves d\u00e9pendante de l\u2019intensit\u00e9 du courant n\u2019a \u00e9t\u00e9 observ\u00e9e.<sup>2<\/sup><\/p>\n<p>Important : la TES ne gu\u00e9rit pas la RP. Des \u00e9tudes ont toutefois montr\u00e9 qu\u2019elle peut ralentir la perte du champ visuel. Discutez avec votre m\u00e9decin traitant afin de d\u00e9terminer si une th\u00e9rapie TES peut \u00eatre envisag\u00e9e dans votre situation.<sup>2<\/sup>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row unlock_row_content=\u00a0\u00bbyes\u00a0\u00bb row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb0&Prime; top_padding=\u00a0\u00bb3&Prime; bottom_padding=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; equal_height=\u00a0\u00bbyes\u00a0\u00bb gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; cvc_maxwidth=\u00a0\u00bb1920&Prime; uncode_shortcode_id=\u00a0\u00bb490954&Prime;][vc_column column_width_percent=\u00a0\u00bb70&Prime; position_vertical=\u00a0\u00bbmiddle\u00a0\u00bb gutter_size=\u00a0\u00bb3&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb column_padding=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; shift_x=\u00a0\u00bb0&Prime; shift_y=\u00a0\u00bb0&Prime; shift_y_down=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; medium_width=\u00a0\u00bb0&Prime; mobile_width=\u00a0\u00bb0&Prime; width=\u00a0\u00bb1\/1&Prime; uncode_shortcode_id=\u00a0\u00bb126108&Prime;][vc_custom_heading heading_semantic=\u00a0\u00bbh3&Prime; text_size=\u00a0\u00bbh3&Prime; uncode_shortcode_id=\u00a0\u00bb188569&Prime;]Qu\u2019est-ce que cela signifie pour les personnes concern\u00e9es ?[\/vc_custom_heading][vc_column_text uncode_shortcode_id=\u00a0\u00bb142718&Prime;]<\/p>\n<ul>\n<li>D\u00e9finir des attentes r\u00e9alistes : la RP \u00e9volue de mani\u00e8re h\u00e9t\u00e9rog\u00e8ne. Le champ visuel diminue en moyenne d\u2019environ 5 \u00e0 17 % par an \u2013 les \u00e9volutions individuelles peuvent varier. Des mesures comparables (m\u00eame m\u00e9thode\/m\u00eame conditions) sont d\u00e9terminantes.<sup>2<\/sup>  <\/li>\n<li>V\u00e9rifier la g\u00e9n\u00e9tique : un test g\u00e9n\u00e9tique peut ouvrir des options th\u00e9rapeutiques et des voies d\u2019acc\u00e8s \u00e0 des \u00e9tudes, et aide au conseil familial.<sup>1<\/sup><\/li>\n<li>Renforcer activement la qualit\u00e9 de vie : la recherche montre des contraintes importantes au quotidien et sur la participation (mobilit\u00e9, travail, sant\u00e9 psychique). La r\u00e9\u00e9ducation, les aides techniques et le conseil sont donc utiles pr\u00e9cocement.<sup>1<\/sup> <\/li>\n<li>Conna\u00eetre les options sp\u00e9cifiques : en cas de mutation RPE65, une th\u00e9rapie g\u00e9nique peut \u00eatre envisag\u00e9e ; pour de nombreuses autres formes, les \u00e9tudes cliniques sont importantes.<sup>1<\/sup><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb2&Prime; top_padding=\u00a0\u00bb3&Prime; bottom_padding=\u00a0\u00bb3&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb609480&Prime;][vc_column width=\u00a0\u00bb1\/1&Prime;][vc_separator uncode_shortcode_id=\u00a0\u00bb100849&Prime; sep_color_type=\u00a0\u00bbuncode-solid\u00a0\u00bb sep_color_solid=\u00a0\u00bb#cddfed\u00a0\u00bb][vc_custom_heading heading_semantic=\u00a0\u00bbh6&Prime; text_size=\u00a0\u00bbh4&Prime; uncode_shortcode_id=\u00a0\u00bb493566&Prime;]R\u00e9f\u00e9rences[\/vc_custom_heading][vc_column_text text_lead=\u00a0\u00bbsmall\u00a0\u00bb uncode_shortcode_id=\u00a0\u00bb203763&Prime;]1 Cross N et al. Retinitis Pigmentosa: Burden of Disease and Current Unmet Needs. Clin Ophthalmol. 2022;16:1993\u20132010.   <\/p>\n<p>2 Stett A et al. TcES dose-dependently slows visual field loss in RP.  TVST. 2023;12(2):29. (Contexte d\u2019histoire naturelle : ADR ~5\u201317 %.)[\/vc_column_text][\/vc_column][\/vc_row][vc_row row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb2&Prime; top_padding=\u00a0\u00bb3&Prime; bottom_padding=\u00a0\u00bb3&Prime; back_color=\u00a0\u00bbcolor-206913&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb118356&Prime; back_color_type=\u00a0\u00bbuncode-palette\u00a0\u00bb][vc_column column_width_percent=\u00a0\u00bb100&Prime; align_horizontal=\u00a0\u00bbalign_center\u00a0\u00bb gutter_size=\u00a0\u00bb4&Prime; overlay_alpha=\u00a0\u00bb50&Prime; shift_x=\u00a0\u00bb0&Prime; shift_y=\u00a0\u00bb0&Prime; shift_y_down=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; medium_width=\u00a0\u00bb0&Prime; mobile_width=\u00a0\u00bb0&Prime; width=\u00a0\u00bb1\/1&Prime; uncode_shortcode_id=\u00a0\u00bb152446&Prime;][vc_custom_heading text_font=\u00a0\u00bbfont-714446&Prime; text_size=\u00a0\u00bbfontsize-914237&Prime; text_weight=\u00a0\u00bb300&Prime; uncode_shortcode_id=\u00a0\u00bb109998&Prime;]Tout savoir sur la th\u00e9rapie,<br \/>\nla recherche clinique et Okuvision[\/vc_custom_heading][vc_row_inner][vc_column_inner width=\u00a0\u00bb1\/1&Prime;][uncode_index el_id=\u00a0\u00bbindex-974899&Prime; index_type=\u00a0\u00bbcarousel\u00a0\u00bb loop=\u00a0\u00bbsize:3|order_by:date|post_type:post|categories:88|taxonomy_count:10&Prime; carousel_lg=\u00a0\u00bb3&Prime; carousel_md=\u00a0\u00bb2&Prime; carousel_sm=\u00a0\u00bb1&Prime; thumb_size=\u00a0\u00bbsixteen-nine\u00a0\u00bb gutter_size=\u00a0\u00bb3&Prime; post_items=\u00a0\u00bbmedia|featured|onpost|original,date,title|-,text|excerpt|200,category|colorbg|relative|display-icon\u00a0\u00bb carousel_height=\u00a0\u00bbequal\u00a0\u00bb carousel_interval=\u00a0\u00bb3000&Prime; carousel_navspeed=\u00a0\u00bb400&Prime; advanced_nav=\u00a0\u00bbyes\u00a0\u00bb el_id1=\u00a0\u00bbindex-974899&Prime; stage_padding=\u00a0\u00bb0&Prime; single_back_color=\u00a0\u00bbcolor-942029&Prime; single_overlay_opacity=\u00a0\u00bb50&Prime; single_padding=\u00a0\u00bb2&Prime; single_title_dimension=\u00a0\u00bbh4&Prime; single_border=\u00a0\u00bbyes\u00a0\u00bb uncode_shortcode_id=\u00a0\u00bb175973&Prime;][uncode_carousel_nav padding=\u00a0\u00bb0&Prime; h_align=\u00a0\u00bbcenter\u00a0\u00bb hide_arrows=\u00a0\u00bbyes\u00a0\u00bb dots_style=\u00a0\u00bblines\u00a0\u00bb hide_counter=\u00a0\u00bbyes\u00a0\u00bb uncode_shortcode_id=\u00a0\u00bb207978&Prime; target=\u00a0\u00bbindex-974899&Prime; dot_single_width=\u00a0\u00bb12&Prime; dot_single_active=\u00a0\u00bb24&Prime; dot_single_height=\u00a0\u00bb12&Prime; dot_single_radius=\u00a0\u00bb999&Prime;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row unlock_row_content=\u00a0\u00bbyes\u00a0\u00bb row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb0&Prime; top_padding=\u00a0\u00bb0&Prime; bottom_padding=\u00a0\u00bb0&Prime; back_color=\u00a0\u00bbcolor-206913&Prime; overlay_alpha=\u00a0\u00bb50&Prime; gutter_size=\u00a0\u00bb3&Prime; column_width_percent=\u00a0\u00bb100&Prime; shift_y=\u00a0\u00bb0&Prime; z_index=\u00a0\u00bb0&Prime; content_parallax=\u00a0\u00bb0&Prime; uncode_shortcode_id=\u00a0\u00bb126459&Prime; back_color_type=\u00a0\u00bbuncode-palette\u00a0\u00bb][vc_column width=\u00a0\u00bb1\/1&Prime;][\/vc_column][\/vc_row][vc_row row_height_percent=\u00a0\u00bb0&Prime; override_padding=\u00a0\u00bbyes\u00a0\u00bb h_padding=\u00a0\u00bb2&Prime; [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2678","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>R\u00e9tinite pigmentaire : aper\u00e7u des \u00e9tudes et de la recherche<\/title>\n<meta name=\"description\" content=\"Recherche actuelle sur la RP : g\u00e9n\u00e9tique, \u00e9volution, qualit\u00e9 de vie. 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